Stuffing several medications into a “polypill” could aid compliance and improve health over expecting patients to take multiple pills, a U.S. study suggests.

The American Heart Association-funded study took place at a community clinic in Alabama. Half got a polypill containing a combination of four meds to treat cholesterol and blood pressure. The other half got the exact same drugs, but in the usual four pills.

The polypill group had remarkably better blood pressure and LDL cholesterol after a year, and they were likelier to still be taking their meds. Lead researcher Daniel Munoz of Vanderbilt told The Independent that the polypill group had a 25% lower chance of a cardiovascular event. He said he hoped his experiment would persuade health officials to look for more innovative ways to make it simpler to take needed medications.


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